What is Zavesca used for?
Zavesca is used to treat adults with mild to moderate type I Gaucher disease. Zavesca is only used in patients
who cannot be treated with enzyme replacement therapy. Zavesca has not been studied in children under 18 years of age.
Type I Gaucher disease is an inherited disease that you get from both your parents. People with Type I Gaucher disease are
missing an enzyme that breaks down a chemical in the body called glucosylceramide. Too much glucosylceramide causes liver
and spleen enlargement, changes in the blood, and bone disease. Zavesca may stop glucosylceramide from forming.
should not take Zavesca?
Do not take Zavesca if you are allergic to any of its ingredients. The active ingredient is
Special Warnings with Zavesca:Do not get pregnant while taking Zavesca. Men and women should use effective birth control during treatment
with Zavesca. Men should keep using effective birth control for 3 months after treatment with Zavesca stops.
General Precautions with Zavesca:
- Zavesca can cause problems affecting your nerves (neurologic problems). It may cause hand tremors (shaky movements), or
worsening of a hand tremor that you already have.
- Zavesca may also cause numbness and tingling in your hands, arms, legs, or feet (peripheral neuropathy).
What should I tell my doctor or health care provider?
Tell your doctor before taking Zavesca:
- if you are pregnant or planning to become pregnant, or if your partner can become pregnant.
Zavesca may harm your baby. Zavesca may also harm a manís sperm.
- if you are breast-feeding.
- about all of your medical conditions.
- about all the medicines you take, including prescription and
non-prescription medicines, vitamins, and other dietary supplements.
Some medicines may affect Zavesca, and Zavesca may affect other
What are some possible side effects of Zavesca? (This is NOT
a complete list of side effects reported with Zavesca. Your health care provider can
discuss with you a more complete list of side effects.)
Diarrhea is the most common side effect for people taking Zavesca. You may also lose weight when you
start treatment with Zavesca. Some of the other side effects of Zavesca include:
- Stomach pain
- Muscle cramps
- Do not feel like eating
- Vision problems
- Low platelet count
For more detailed information about Zavesca, ask your health care provider.